Infertility and Polycystic ovary syndrome

Main amenorrhea is the failure of menses to arise by age 16 years, in the presence of normal growth and secondary sexual characteristics. Anovulation is a not a syndrome but a signal, in the same way that polycystic ovaries are the manifestation of a major infection process. Infertility affects around 13-14% of reproductive-aged couples. It is well-defined as the failure to conceive after 1 year of suitably timed, unprotected intercourse. About 1-2% of women with unsuitably managed an ovulatory bleeding eventually may produce endometrial cancer. Polycystic ovary syndrome may result from abnormal function of the hypothalamic-pituitary-ovarian (HPO) axis. A woman is identified with polycystic ovaries, if she has 12 or more follicles in at least 1 ovary.